Does spironolactone cause insomnia

Does spironolactone cause insomnia DEFAULT

How Prescription Drugs Almost Killed me and Took Years of my Life

I&#;ve told my story about my experience with anxiety and insomnia a few times here on the blog (and here&#;s a post describing my favorite resources for overcoming it)&#; but I&#;ve never told it completely, in full. Plus, I keep learning more about what happened to me, so I keep developing a better picture of what&#;s going on.

Below is more of my story. I am sharing it with you mostly because I want you to know that health is not easy for any of us, health bloggers included. I also want you to know that you are not alone in whatever struggles you face. And also I want to give you hope, because I had no hope. I never thought things would get better.  But then they did. They really, I still can hardly believe it, did. They&#;re not perfect these days, but god, they&#;re so, so sweetly better.

Here it is, my life on a plate:

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After I spent a summer in Italy living off of almost nothing but cheese and being incredibly skinny, I developed a serious case of acne.

(facepalm)

For years afterward the acne was nearly impossible to manage. Some days I didn&#;t even leave my room, because I didn&#;t want to inflict my appearance on people. I was doing them a service, I was convinced. I did my best to fix the acne  (I even ate paleo!), yet nothing appeared to make much of a dent at all.

(If you are struggling with acne, I have an awesome FREE guide on clearer skin in 7 days, all you have to do is sign up for my newsletter!)

Deep down, I knew that I had to gain weight to be healthier and to clear up my skin. But I didn&#;t want to. &#;Please don&#;t make me get fat, please don&#;t make me get fat&#; I&#;d chant over and over again in my head sometimes while going to sleep. I had the &#;ideal&#; body. There was no way I was going to give that up, come hell or high water.

In January of , I was desperate enough to stay thin and clear my skin that I tried prescription meds for the acne.

So then came the hell, and the high water.

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The drug I took is called &#;spironolactone.&#;Spiro was not originally designed to treat hormonal acne. It is, in fact, a blood-pressure medication. It also just so happens to have a dampening effect on male sex hormone production, so it is often prescribed off-label to women with acne.

WebMD lists spiro&#;s potential side effects as dizziness, drowsiness, lightheadedness, stomach upset, nausea, or headache. Not too bad, right? BUT it also warns that spironolactone can cause potassium levels to build up in the blood. If this happens, muscle weakness and heart failure may occur.

Heart failure.

To prevent this disastrous possibility from killing off wide swaths of the female population, doctors usually insist on getting blood potassium levels tested before prescribing spironolactone.

I got my blood tested a few weeks after going on spiro, and my potassium levels checked out &#;fine.&#;

&#;-

In February of , I stopped sleeping well. In fact, I almost stopped sleeping completely. To be fair, I have always been a poor sleeper, having to wait several hours some nights to fall asleep. But this February brought, for the first time in my life, entire nights without sleep. I will never forget my am seminars every Wednesday morning on one hour of sleep. Nor will I forget the terrified and confused tears that came later in the afternoons. Nor will I forget the morning I had to take the GRE on 25 minutes of sleep. Nor will I forget the tears of exhausted frustration I wept for days after. (Still aced it, btw!) These are tears that I still, to this day, experience after a poor night&#;s rest.

I also developed a severe case of anxiety. To be fair, again, I have always been a bit neurotic. But this February, for the first time in my life, I laid awake in bed at 3am and felt the ceiling collapsing down on me, suffocating me, with my heart racing, desperate and afraid. Afraid doesn&#;t cut it. Panicked. Terrified.I&#;d call my mother sobbing. &#;I don&#;t know what&#;s wrong, I don&#;t know what&#;s wrong, I don&#;t know what&#;s wrong,&#; I&#;d gasp. She&#;d talk to me and tell me everything was okay for hours, sometimes until the sun came up. At which point she would leave the house for her full-time job.

My mother is a saint.

I stopped taking thyroid meds. I guess that helped. My potassium levels continued to check out fine. Plus, for all the thousands of reviews of spironolactone available online, % (there are more than of them, and I found 2) of them mention anxiety as a side effect. None mention insomnia. It seemed it had to be something else.

Yet finally in June I was at my wits end. Even though I was scared shitless to go off of Spiro because my acne would come roaring back, I went back to my mother&#;s home in Michigan, hid my face in my bedroom, and did the experiment. I went off the spiro.

The anxiety calmed. The sleeplessness abated. Somewhat. I breathed. For the first time in four months, I breathed. Relief was on the horizon.

Then, on the evening of June 20, I did not sleep.

Nor did I on June

Or June

Or 23rd.

I crawled into my mother&#;s bed, crying. I got a few hours of fitfull sleep.

I had to come back to Boston. I didn&#;t want to. But work called. My life called. I wasn&#;t about to let my insanity destroy my life.

&#;&#;

From there things got nothing but worse. I would lay on the sofa with my heart beating like a jackhammer against my rib cage. I felt claustrophobic and trapped. I&#;d keep the front door wide open, and I&#;d lay there and just hate how few windows there were in the living room. I felt overexposed. I&#;d go outside, and I&#;d hate how open the sky was.

I couldn&#;t win. Nothing felt good.

I&#;d try to pick a shirt to wear before work in the mornings, and was it blue or red? 20 minutes and a panic attack later, I&#;d hyperventilate my way out the door in one color or the other&#; of course it didn&#;t matter, in the end.

I don&#;t know how to explain the intensity of anxiety to people who have never experienced it. I wouldn&#;t wish it on my worst enemies. Perhaps this&#;ll put it in perspective: Sometimes I suffer debilitating migraines &#; the ones that make you throw up and kind of wish you were dead they hurt so bad. Today, I don&#;t know if I&#;d rather have the migraines or the anxiety.

What anxiety does to a brain like mine is astounding. I am a human being who weighs every pro and con and implication before making a decision. I see and I know very many things. Already my neurons are a web of highly nuanced, carefully chosen concerns. The horror of anxiety is that it sets them on fire.

Thoughts race in a million directions. Every question makes more questions arise, and the most horrible of them rocket to the surface and drag you cartwheeling down their own sinister nightmares before you can take just one breath. It is relentless. And hopeless. And endless.

What&#;s more:

You know that feeling where you&#;re nervous, and your heart starts to beat like a bass drum on speed, and you can feel it in your chest and maybe even sometimes in your ears? My anxiety&#;s partner in crime is a heart on a murderous rampage. The palpitations never go away. My heart&#;s its own monster, it&#;s own hell. It really beats so hard. At least it used to. These days it doesn&#;t happen too often. And yet again &#; it is nothing compared to the anxiety that rides wild on its back.

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With these kinds of health issues, it&#;s nearly impossible to make a decision without being paralyzed by fear. It&#;s nearly impossible to calm the body enough to sleep. It&#;s nearly impossible to see anything but relentless terror in the future. I think I&#;ve probably made this point clear.

Which is why, in August of , riding my bike down Massachusetts Avenue to an acupuncture appointmentof all things, I very, percent sincerely, for the only time in my life, genuinely wanted to stop living.

This was the first time prescription drugs almost killed me.

The second was perhaps a week later. I finally re-connected the dots. I looked at the symptoms of high potassium levels &#; heart palpitations, shortness of breath, muscle weakness &#; and thought, &#;holy hell, I&#;ve still got it.&#;

I checked myself into the ER. They took me right in. My pulse, they said, was shockingly hard and fast.

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Yet in the ER, my blood tests came back fine. My EKG came back fine. Everything came back fine. I snatched my test results out of my attending physician&#;s hands and knew right away that my electrolyte levels were fishy, despite his insistance that they were fine.

I gave up sodium for a day or two and felt a bit better. Every once in a while I&#;d do that and feel a bit better. But nothing improved.

10 months of chronic anxiety, panic,  heart irregularity, and sleepless nights later, I realized that my symptoms lined up perfectly with those listed for magnesium deficiency, right down to insensitivity to noise. (That morning, I had laid in bed crying because I could hear my roommate&#;s air conditioner running.) One teaspoon of magnesium later (this is my favorite, by the way), and I felt miraculously better. Really, it felt like a miracle. Thump..thump&#;..thump&#; my heart slowed. Through the darkness peeked genuine hope for the first time in months.

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&#;Just kidding!&#; said life. I had been wrong. I supplemented the hell out of magnesium for months but the anxiety, insomnia, and heart racing never really went away.

It was not until another year later, in February of , when I ate an avocado (a high potassium food) and my heart started pounding, that I connected the dots on what had actually happened:

My kidneys started sparing potassium back in January , and, even though I stopped taking spironolactone six months later, the potassium sparing never stopped.

High potassium causes irregular heartbeat, muscle weakness, insomnia, anxiety.  Blood tests and doctors and discussion boards all said I was okay on the spiro. But I wasn&#;t. They said I would definitely be fine coming off of it, but I wasn&#;t.  Yesterday, I ate an avocado. I won&#;t dare eat one today. Finally, now  in the fall of , I know specifically how much potassium I can consume without making my heart race. It&#;s not much.

I also now know, after doing extensive research, that the precise effect spironolactone has on the kidneys actually up-regulates excitatory activity in the brain. It increases glutamate and decreases GABA. This causes anxiety. I figured this out and almost solved my health problems for good when I began supplementing with GABA and my migraines and anxiety abated&#;for the first time in years. (This is on of the GABA supplements I like) The whole story and it&#;s horrible villain is now crystal clear: spironolactone stole my peace of mind, and maybe even my sanity, at least a little bit, for years.

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Spironolactone has been the primary influence on the quality of my life for the last 34 months. Throughout that time, it never won the war. I wrote a few books. I got a degree. I had my willingness to keep pushing forward in life bolstered by my discovery of partner dancing, which truly was, as my mother continues to insist, what really saved my life. Today, I can happily say that I am at peace, and relatively carefree, and excited about the future, and maybe even genuinely happy, most of the time. I figured it out. I really did. It took me so long, and it was so hard, but I made it. I figured it out. My health problem had a cause&#; I just had to stay committed to recovery and doing everything I could to find the cure I needed.

But I will say that the spiro won way more of the battles than I&#;d like. My life during those two and half years was at times unbearably difficult. I don&#;t know how long my heart will be prone to beating like this. I still sleep extraordinarily poorly. I don&#;t eat like a normal person, nor do I make plans or schedule my life like a normal person.  Yet perhaps worst of all  is that spiro stole my innocence. Spiro took me to the dark side of what a human mind can feel and do. I am incapable of forgetting just how terribly, insidiously dark that is.

This is the story of the drug that killed me.

Almost.

🙂

(For help with anxiety &#; well, I&#;m writing a book on it now, but I also highly recommend this book &#; it is the go-to anxiety-manager for psychologists who know their stuff.  The Mood Cure and The Anti-Anxiety Food Solution are all fantastic reads as well.  And if you&#;re interested: GABA and Magnesium both can help with anxiety.  Find GABA supplement here.  Find magnesium here. )

How Acne Medication Almost Killed Me (and took years of my life)

Sours: https://www.healthtoempower.com/how-prescription-drugs-almost-killed-me-and-stole-years-of-my-life/

Spironolactone, Oral Tablet

Highlights for spironolactone

  1. Spironolactone oral tablet is available as a brand-name drug and a generic drug. Brand name: Aldactone.
  2. Spironolactone comes as an oral tablet and an oral suspension.
  3. Spironolactone is used to reduce swelling from liver disease and nephrotic syndrome. It’s also used to treat high blood pressure, heart failure, and excessive aldosterone secretion.

Important warnings

  • Potassium intake: This drug can cause hyperkalemia (high potassium levels). While taking this drug, you should watch your potassium intake. You shouldn’t take potassium supplements, eat a diet rich in potassium, or consume salt substitutes containing potassium. Having too much potassium in your body can lead to severe problems. This can even be fatal. Talk with your doctor or a nutritionist if you’re concerned about your potassium intake.
  • Enlarged breasts: This drug may cause you to have enlarged breasts (gynecomastia). This can happen in both men and women. If this happens, your doctor may stop your treatment with this drug. This symptom usually goes away once you stop taking this drug.
  • Low blood pressure and worsening kidney function: This drug may result in low blood pressure and worsening kidney function. Your doctor will monitor your blood pressure and kidney function while you take this drug.

What is spironolactone?

Spironolactone is a prescription drug. It comes as an oral tablet and an oral suspension.

Spironolactone oral tablet is available as the brand-name drug Aldactone and as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in all strengths or forms as the brand-name drug.

This drug may be taken as part of a combination therapy with other medications.

Why it’s used

This drug is used to reduce swelling from liver disease and nephrotic syndrome (a kidney problem). It’s also used to treat high blood pressure, heart failure, and hyperaldosteronism (excessive secretion of the hormone aldosterone).

How it works

This drug belongs to a class of drugs called aldosterone antagonists (blockers), or potassium-sparing diuretics. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

This drug works by blocking aldosterone activity. Aldosterone is a chemical made by the body that can cause water retention. This makes certain heart, kidney, and liver conditions worse. By blocking aldosterone, your body won’t retain fluid. This process also stops potassium from being excreted by your body.

This drug may lower your blood pressure by blocking aldosterone’s effect on your blood vessels.

Spironolactone side effects

Spironolactone oral tablet may cause drowsiness. You shouldn’t drive, use machinery, or do similar tasks that require alertness until you know how this drug affects you.

This drug can also cause other side effects.

More common side effects

The more common side effects that can occur with spironolactone include:

  • diarrhea and abdominal cramping
  • nausea and vomiting
  • high potassium levels
  • leg cramps
  • headache
  • dizziness
  • drowsiness
  • itching
  • irregular menstrual cycles or bleeding after menopause

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk with your doctor or pharmacist.

Serious side effects

Call your doctor right away if you have serious side effects. Call if your symptoms feel life threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

  • Allergic reactions. Symptoms can include:
    • skin rash
    • hives
    • fever
    • trouble breathing
    • swelling of your lips, mouth, tongue, or throat
  • Electrolyte and/or fluid problems. Symptoms can include:
    • mouth dryness
    • extreme thirst
    • extreme weakness and tiredness
    • fast heart rate and dizziness
    • not being able to urinate
  • Dangerously high potassium levels. Symptoms can include:
    • muscle weakness
    • not being able to move your legs and arms
    • extreme tiredness
    • tingling or numb feeling in your hands or feet
    • slow heart rate
  • Breast enlargement (gynecomastia). Symptoms can include:
    • growth of breast tissue in males and females
  • Severe skin reactions. Symptoms can include:
    • redness, blistering, peeling, or loosening of your skin, including inside of your mouth

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.

Spironolactone may interact with other medications

Spironolactone oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk with your doctor or pharmacist.

Examples of drugs that can cause interactions with spironolactone are listed below.

Drugs and supplements that increase potassium blood levels

Taking certain medications with spironolactone can increase the amount of potassium in your body to unsafe levels. Examples of these drugs include:

  • angiotensin-converting enzyme (ACE) inhibitors, such as:
    • benazepril
    • captopril
    • enalapril
    • fosinopril
    • moexipril
    • perindopril
    • quinapril
    • ramipril
    • trandolapril
  • angiotensin II receptor blockers (ARBs), such as:
    • irbesartan
    • losartan
    • olmesartan
    • telmisartan
    • valsartan
  • direct renin inhibitors, such as:
  • heparin and low molecular weight heparin (LMWH)
  • potassium supplements
  • potassium-sparing diuretics, such as:
    • triamterene
    • eplerenone (This drug should not be used with spironolactone.)

Pain drugs

Taking certain pain drugs with spironolactone can result in kidney damage and increased blood pressure. Examples of these pain drugs include:

  • nonsteroidal anti-inflammatory drugs (NSAIDs), such as:
    • diclofenac
    • ibuprofen
    • indomethacin
    • ketoprofen
    • ketorolac
    • meloxicam
    • nabumetone
    • naproxen
    • piroxicam

Cholesterol drugs

Taking certain cholesterol drugs with spironolactone can increase the amount of potassium and acid in your body to unsafe levels. Examples of these drugs include:

Lithium

Taking lithium with spironolactone can increase the effects of lithium. Your doctor may lower your dosage of lithium if you take these drugs together.

Digoxin

Taking digoxin with spironolactone may increase the effects of digoxin. Your doctor may monitor you closely if you take these drugs together.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare professional about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

Spironolactone warnings

This drug comes with several warnings.

Allergy warning

This drug can cause a severe allergic reaction. Symptoms include:

  • trouble breathing
  • swelling of your throat or tongue
  • hives

Call or go to the nearest emergency room if you develop these symptoms.

Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).

Warnings for people with certain health conditions

For people with liver disease: Taking this drug when you have liver disease may lead to a coma. Tell your doctor right away if you have the following symptoms, which may be signs of hepatic coma:

  • confusion
  • poor judgment
  • foggy memory
  • abnormal body movements and shaking
  • trouble concentrating

For people with hyperkalemia: You shouldn’t take this drug if you have hyperkalemia (high potassium levels). It can worsen the condition.

For people with kidney disease: You’re at increased risk of side effects from this drug. You’re also at increased risk of hyperkalemia (high potassium levels). If you take this drug, you should monitor your potassium levels closely. Your doctor can check your potassium levels using a blood test.

For people with Addison’s disease: You shouldn’t take this drug if you have Addison’s disease. It can make your illness worse.

For people with heart disease: Don’t take potassium supplements, eat a diet high in potassium, or take drugs that increase potassium levels if you have heart failure and you’re taking this drug. Dangerously high potassium levels are more likely if you have heart failure. This can be fatal.

Warnings for other groups

For pregnant women: Research in pregnant animals has shown negative effects to the fetus when the mother takes the drug. However, there haven’t been enough studies done in humans to be certain how the drug might affect a fetus.

Despite this lack of research, this drug should be used during pregnancy only if the potential benefit justifies the potential risk. Tell your doctor if you’re pregnant or plan to become pregnant. If you become pregnant while taking this drug, call your doctor right away.

For women who are breastfeeding: A metabolite (substance that results from the breakdown of a drug) from spironolactone passes into breast milk. This may cause side effects in a child who is breastfed. Talk with your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication.

For seniors: Older adults may process drugs more slowly. A normal adult dose may cause levels of this drug to be higher than normal. If you’re a senior, you may need a lower dose or a different schedule.

For children: This medication shouldn’t be used in children younger than 18 years.

How to take spironolactone

All possible dosages and forms may not be included here. Your doctor will tell you what dosage is right for you. Your dose, form, and how often you take it will depend on:

  • your age
  • the condition being treated
  • how severe your condition is
  • other medical conditions you have
  • how you react to the first dose

Drug forms and strengths

Generic: Spironolactone

  • Form: oral tablet
  • Strengths: 25 mg, 50 mg, mg

Brand: Aldactone

  • Form: oral tablet
  • Strengths: 25 mg, 50 mg, mg

Dosage for high blood pressure (hypertension)

Adult dosage (ages 18–64 years)

The typical starting dosage is 25– mg taken by mouth each day. It’s given as a single dose or split into two doses.

Child dosage (ages 0–17 years)

This medication isn’t approved for use in children younger than 18 years.

Senior dosage (ages 65 years and older)

There are no specific recommendations for senior dosing. Older adults may process drugs more slowly. A normal adult dose may cause levels of this drug to be higher than normal in your body. If you’re a senior, you may need a lower dose or a different dosage schedule.

Dosage for swelling (edema) from nephrotic syndrome and liver disease

Adult dosage (ages 18–64 years)

The typical starting dosage is mg taken by mouth each day. It’s given as a single dose or split into two doses. Some people may take as little as 25 mg per day or as much as mg per day.

Child dosage (ages 0–17 years)

This medication isn’t approved for use in children younger than 18 years.

Senior dosage (ages 65 years and older)

There are no specific recommendations for senior dosing. Older adults may process drugs more slowly. A normal adult dose may cause levels of this drug to be higher than normal in your body. If you’re a senior, you may need a lower dose or a different dosage schedule.

Dosage for heart failure

Adult dosage (ages 18–64 years)

The typical starting dosage is 25 mg taken by mouth once per day. Your doctor may increase or decrease your dosage based on how you respond to the drug. Some people may take 50 mg once per day, and others may take 25 mg once every other day.

Child dosage (ages 0–17 years)

This medication isn’t approved for use in children younger than 18 years.

Senior dosage (ages 65 years and older)

There are no specific recommendations for senior dosing. Older adults may process drugs more slowly. A normal adult dose may cause levels of this drug to be higher than normal in your body. If you’re a senior, you may need a lower dose or a different dosage schedule.

Dosage for excessive aldosterone secretion

Adult dosage (ages 18–64 years)

The typical dosage is to mg daily in preparation for surgery. If you cannot have surgery, your doctor may give you the lowest effective dose of this drug long term.

Child dosage (ages 0–17 years)

This medication isn’t approved for use in children younger than 18 years.

Senior dosage (ages 65 years and older)

There are no specific recommendations for senior dosing. Older adults may process drugs more slowly. A normal adult dose may cause levels of this drug to be higher than normal in your body. If you’re a senior, you may need a lower dose or a different dosage schedule.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you.

Take as directed

Spironolactone is used for long-term treatment. It comes with serious risks if you don’t take it as prescribed.

If you don’t take it at all: If you do not take this drug, your blood pressure will stay high. This can lead to a heart attack or stroke. Your body may also become overloaded with fluid. This can cause serious worsening of kidney and liver disease.

If you stop taking it suddenly: If you stop taking this drug, you may start retaining water. You may also have a sudden increase in your blood pressure. This can lead to a heart attack or stroke.

If you don’t take it on schedule: If you don’t take this drug on schedule, your blood pressure might not be controlled. This can lead to a heart attack or stroke.

What to do if you miss a dose: If you forget to take your dose, take it as soon as you remember. If it’s just a few hours before the time for your next dose, then wait and only take one dose at that time. Never try to catch up by taking two doses at once. This could cause dangerous side effects.

If you take too much: If you take too much of this drug, you may have the following symptoms:

  • drowsiness
  • confusion
  • skin rash
  • nausea
  • vomiting
  • dizziness
  • diarrhea
  • changes in your body’s electrolytes, which can cause irregular heart rate or muscle pain and cramping

If you think you’ve taken too much of this drug, call your doctor or local poison control center. If your symptoms are severe, call or go to the nearest emergency room right away.

How to tell the drug is working: You may not be able to tell whether this drug is working or not. It’s important that you take your medication every day as directed by your doctor. Your doctor will monitor your condition and be able to tell if this drug is working. You may need to buy your own blood pressure monitor to check your blood pressure at home.

Important considerations for taking spironolactone

Keep these considerations in mind if your doctor prescribes spironolactone for you.

General

  • This drug can be taken with or without food.

Storage

  • Store spironolactone at room temperature between 68°F and 77°F (20°C and 25°C).
  • Don’t freeze this drug.
  • Keep it away from light.
  • Keep it away from high temperature.
  • Don’t store this medication in moist or damp areas, such as bathrooms.

Refills

A prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.

Travel

When traveling with your medication:

  • Always carry your medication with you. When flying, never put it into a checked bag. Keep it in your carry-on bag.
  • Don’t worry about airport X-ray machines. They can’t hurt your medication.
  • You may need to show airport staff the pharmacy label for your medication. Always carry the original prescription-labeled box with you.
  • Don’t put this medication in your car’s glove compartment or leave it in the car. Be sure to avoid doing this when the weather is very hot or very cold.

Self-management

You may need to check your blood pressure at home using a blood pressure monitor. You should keep a log with the date, time of day, and your blood pressure readings. Bring this diary with you to your doctor appointments.

Clinical monitoring

While you’re taking this drug, your doctor will check the following:

  • heart function
  • kidney function
  • liver function
  • electrolytes
  • blood pressure

Hidden costs

You may need to purchase a home blood pressure monitor to check your blood pressure at home. These are available for purchase at most pharmacies.

Prior authorization

Many insurance companies require a prior authorization for this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription.

Are there any alternatives?

There are other drugs available to treat your condition. Some may be better suited for you than others. Talk with your doctor about other options that may work for you.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

Sours: https://www.healthline.com/health/drugs/spironolactone-oral-tablet
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4. SSRI antidepressants

Why they're prescribed: SSRIs (selective serotonin-reuptake inhibitors) are used to treat symptoms of moderate to severe depression. SSRIs block the reabsorption (reuptake) of the neurotransmitter serotonin in the brain, which may help brain cells send and receive chemical messages, easing depression. They're called selective because they seem to primarily affect serotonin, not other neurotransmitters.

Examples: citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil, Pexeva) and sertraline (Zoloft).

How they can cause insomnia: Just as it isn't known exactly how SSRIs work, it isn't known exactly how these drugs interfere with sleep. Studies have shown, however, that SSRIs cause agitation, insomnia, mild tremor and impulsivity in 10 percent to 20 percent of the people who take them.

Although about half of people who take SSRIs say that the drugs make them feel better, many continue to struggle with symptoms that can make life miserable, especially insomnia. We know this from researchers at the University of Texas Southwestern Medical Center in Dallas, who combed through data from the STAR*D trial, the largest and longest study ever done on depression treatment, and published their findings in Almost all of the subjects in the Star*D trial, which was funded by the National Institute of Mental Health, said they continued to have problems with insomnia, with 81 percent reporting being unable to sleep in the middle of the night.

Alternatives: If you are experiencing anxiety or insomnia while on an SSRI (or any other antidepressant, for that matter), it's important to tell your prescribing doctor right away. Sleeplessness — in itself a marker of depression — can make you even more depressed.

Because antidepressants vary in their side effects, a change in dosage or switching to another medication may help you feel better without causing insomnia or other sleep disturbances. A selective serotonin/norepinephrine reuptake inhibitor (SSRI/SNRI), a newer-generation antidepressant, offers some advantages in improving relaxation and sleep. Of the three drugs in this category (clomipramine, duloxetine and venlafaxine), I find venlafaxine to have the least adverse side effects in older patients and to be easier to dose to a therapeutic level.

Many people find that cognitive behavior therapy works just as well as medication. (Cognitive therapy aims to help people overcome their difficulties by changing their thinking, behavior and emotional responses.) Others report success with such approaches as acupuncture, exercise, changes in diet, meditation, relaxation therapy and the like.

Sours: https://www.aarp.org/health/drugs-supplements/info/medications-that-can-cause-insomnia.html

Spironolactone Related Insomnia

Tell us about your Experience with Spironolactone Related Insomnia

Druginformer Identified Side Effects:Headache, Polyuria, Dizziness, Abdominal distension, Amnesia, Insomnia, Muscular weakness, Somnolence, Swelling, Weight increased, Musculoskeletal discomfort, Pco2

Posted By Anonymous in askapatient.com onSeptember 11, @ am

Druginformer Identified Side Effects:Tremor, Feeling cold, Dizziness, Nausea, Night sweats, Nightmare, Anxiety, Dehydration, Depression, Hyperhidrosis, Insomnia, Migraine, Panic attack, Suicidal ideation, Swelling, Weight increased, Hot flush

Posted By Anonymous in askapatient.com onAugust 15, @ am


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Sours: https://www.druginformer.com/search/side_effect_details/spironolactone/insomnia.html

Spironolactone cause insomnia does

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Spironolactone - Mechanism, side effects, precautions

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